cancer illuminationtm visualization

Fluorescence-Guided Imaging for Endoscopic Surgery

What Is Cancer IlluminationTM Technology?

Cancer Illumination visualization is an advanced endoscopic imaging technology that enhances intraoperative visualization of cancerous tissue using a targeted fluorescent agent and near-infrared (NIR) imaging.

Integrated with the Synergy Vision™ imaging system, Cancer Illumination visualization enables real-time fluorescence imaging of potential cancerous lesions that may not be visible under standard white light. This technology is designed to support informed surgical decision-making by helping surgeons identify, localize, and access cancerous tissue with greater confidence during surgical procedures.

Cancer Illumination visualization provides surgeons with real‑time visual information beyond standard endoscopic imaging. By illuminating cancerous lesions during specific procedures, this technology helps identify areas of interest and supports surgical assessment and decision-making.


Accessible directly from the Synergy Vision imaging platform, Cancer Illumination technology fits seamlessly into surgical workflows, enhancing visualization without disrupting workflow efficiency or requiring additional standalone systems.

Enhanced Tumor Visualization

A targeted fluorescent agent causes suspected cancerous tissue to illuminate under NIR imaging, improving visualization of lesions that may otherwise be difficult to see under standard white light.

Fully Integrated Imaging

Cancer Illumination visualization is accessible via the Synergy Vision system, allowing surgeons to switch between imaging modes without changing equipment.

Increased Lesion Detection

Studies have demonstrated an increased percentage of lesions detected with Cancer Illumination visualization that were not identified on preoperative imaging.1,2

Informed Resection Decisions

Real‑time visualization provides additional visual information to support intraoperative assessment during endoscopic procedures.

Why Surgeons Choose
Cancer Illumination Technology

Cancer Illumination visualization is built on a unified imaging platform designed to work as one throughout the procedure. From advanced visualization modes to compatible camera technology and a targeted fluorescent agent, each component integrates seamlessly to support real‑time insight, efficient workflow, and confident intraoperative decision-making during endoscopic surgery.

Designed to Reveal What Standard Imaging May Miss

Products

Fluorescence Imaging Across Specialties

Explore technologies designed to support fluorescence-guided surgery and Cancer Illumination imaging when used with a compatible targeted imaging agent.

Synergy Vision System

The Synergy Vision system is an all-in-one endoscopic imaging platform that supports white light, near-infrared fluorescence, and Cancer Illumination imaging modalities. Surgeons can transition between modes in real time, supporting efficient intraoperative decision-making. As an advanced fluorescence imaging platform, the Synergy Vision system provides direct access to Cancer Illumination technology without requiring separate standalone equipment.

Near-Infrared Imaging

When paired with an approved fluorescent imaging agent, near-infrared (NIR) imaging enables visualization of illuminated, potentially suspicious cancerous lesions during endoscopic procedures. This capability supports enhanced tissue differentiation beyond standard imaging.

Compatible Fluorescent Imaging Agent

Cancer Illumination technology is designed for use with a compatible fluorescent imaging agent. When used with the Synergy Vision platform, this agent enables real-time fluorescence visualization of lesions suspicious for lung or ovarian cancer during select procedures where clinically appropriate.1,2

Accessories

Designed for near-infrared (NIR) visualization, this integrated accessory portfolio supports consistent illumination and imaging from camera head to scope, helping enable clear identification of targeted anatomy during fluorescence-guided procedures.

Synergy Visionary™ Camera Head

Supports 4K and NIR imaging modes

NIR-Compatible Light Source

Enables fluorescence excitation

Bifurcated Light Guide

Delivers consistent illumination to the surgical field

NIR Scopes

Optimized for white light and
fluorescence visualization

Clinical Applications

Cancer Illumination imaging supports real-time fluorescence visualization in select procedures when clinically appropriate. Used with a compatible fluorescent imaging agent on the Synergy Vision platform, it helps surgeons visualize cancerous lesions and targeted anatomy during specific fluorescence-guided procedures.

8%

In 8% of lung cancer patients, surgeons identified additional cancerous lesions intraoperatively that were not detected on preoperative imaging.1
19%

27%

With a specific targeted imaging agent, additional lesions were found in 27% of ovarian cancer patients that were not visible with standard techniques.2
38%

19%

In 19% of patients, a specific targeted imaging agent identified lesions that were not detected using standard white-light imaging or palpation.1

Frequently Asked Questions About Cancer Illumination Technology

Which fluorescent imaging agents can be used with Cancer Illumination technology?

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Cancer Illumination technology is designed for use with a compatible fluorescent imaging agent on the Synergy Vision platform. Refer to applicable product labeling and regulatory clearances for information regarding specific imaging agent compatibility and indications for use. Contact an Arthrex Technology Consultant for additional information.

How is fluorescence-guided surgery used in oncology?

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Fluorescence-guided surgery uses a fluorescent imaging agent paired with near-infrared imaging to help visualize potentially cancerous tissue and targeted anatomy that may not be visible under white light. Cancer Illumination technology delivers this capability on the Synergy Vision platform.

Which types of procedures can be performed with Cancer Illumination technology?

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Cancer Illumination technology is used in select procedures where fluorescence imaging is clinically appropriate and consistent with the intended use of the fluorescent imaging agent.

Can Cancer Illumination technology replace standard endoscopic imaging?

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No. Cancer Illumination technology complements standard white-light imaging by providing additional visual information during the procedure.

Designed for Fluorescence Imaging

Explore integrated visualization technologies that support fluorescence-guided surgery and enhanced intraoperative imaging.

1. On Target Laboratories. Cytalux for Lung Cancer. Accessed August 11, 2026. https://cytalux.com/cytalux-for-lung-cancer/

2. On Target Laboratories. Cytalux for Ovarian Cancer. Accessed August 11, 2026. https://cytalux.com/cytalux-for-ovarian-cancer/